Selkirk Rex — Selkirk autosomal dominant Rex (hereditary; OMIA-verified breed predisposition)

--- license: permission_granted topic_id: companion_breed_health_selkirk_rex_selkirk_autosomal_dominant_rex_cat category: companion-breed-health title: "Selkirk Rex — Selkirk autosomal dominant Rex (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump." source_file: pdf-raw/breed-health/selkirk_rex_selkirk_autosomal_dominant_rex_3375.txt date_parsed: 2026-08-02 tokens_estimated: 84 verification: method: substring_match claims: 5 passed: 5 date: 2026-08-02 recovered: false path: companion-breed-health/companion_breed_health_selkirk_rex_selkirk_autosomal_dominant_rex_cat/01_companion_breed_health_selkirk_rex_selkirk_autosomal_dominant_rex_cat.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Selkirk Rex — Selkirk autosomal dominant Rex (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA001712/9685/" retrieved: "2026-08-02" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false

Selkirk Rex — Selkirk autosomal dominant Rex (hereditary; OMIA-verified breed predisposition)

Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

• Breed: Selkirk Rex (Cat)
• Disorder: Selkirk autosomal dominant Rex
• Mode of inheritance: Autosomal incomplete dominant
• Summary: see also a href=../../../../../../OMIA001581/9685/OMIA:001581-9685/a : Curly coat, Devon rex in Felis catus
• Defect: no

Associated gene(s)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• Gene: Entrez Gene ID 5778227 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
• OMIA molecular-genetics note: By sequencing some of the comparative positional candidate keratin genes described in the Mapping section, Gandolfi et al. (2013) identified the causal mutation as a c.445-1G&gt;C SNP (omia.variant:394) which "likely disrupts the highly conserved acceptor splicing site of intron one." They also reported that "Sequence of the complete RNA transcript revealed that an alternative downstream acceptor …

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• 2012. Selkirk Rex: morphological and genetic characterization of a new cat breed. J Hered — PubMed:PMID22837475 | DOI:10.1093/jhered/ess039 — OMIA Phene_Article / Article
• 2013. A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats. Sci Rep — PubMed:PMID23770706 | DOI:10.1038/srep02000 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

• OMIM:615895 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
• OMIM:608245 (type: gene) — OMIA Group_OMIM (via OMIA_ID)

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."