--- license: permission_granted topic_id: companion_breed_health_schnauzer_standard_omia6303_dog category: companion-breed-health title: "Schnauzer, Standard — Stomatocytosis (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump." source_file: pdf-raw/breed-health/schnauzer_standard_omia6303_6303.txt date_parsed: 2026-08-02 tokens_estimated: 178 verification: method: substring_match claims: 5 passed: 5 date: 2026-08-02 recovered: false path: companion-breed-health/companion_breed_health_schnauzer_standard_omia6303_dog/01_companion_breed_health_schnauzer_standard_omia6303_dog.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Schnauzer, Standard — Stomatocytosis (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA002932/9615/" retrieved: "2026-08-02" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false
Schnauzer, Standard — Stomatocytosis (hereditary; OMIA-verified breed predisposition)
Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Breed: Schnauzer, Standard (Dog)Disorder:Summary: see also a href=../../../../../../OMIA001178/9615/OMIA:001178-9615/a : Stomatocytosis and gastritis in Canis lupus familiaris (dog) and a href=../../../../../../OMIA000300/9615/OMIA:000300-9615/a : Dwarfism with anaemia in Canis lupus familiaris (dog) for other forms of stomatocytosis.Clin feat: Castillo and Williams (2021) report asymptomatic decrease in red blood cells with various morphological changes of the red blood cells (stomatocytes, knizocytes, mild anisocytosis, mild macrocytosis, and mild polychromasia) in a a Beagle and Australian Cattle Dog.Defect: yes
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIA molecular-genetics note: Wallace et al. (2025) conducted whole genome sequencing of an affected Beagle and Australian Cattle Dog: "Genetic variants identified in stomatocytosis cases were compared to WGS variant call sets (CanFam3.1) of 119 control dogs and > 1,000 dogs from public and private datasets ... . ... Cases did not carry coding variants consistent with single-variant monogenic inheritance in genes linked to …
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 2025. Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis. Gene — PubMed:PMID39929273 | DOI:10.1016/j.gene.2025.149314 — OMIA Phene_Article / Article
- 1982. Dwarfism in Alaskan malamutes: a disease resembling metaphyseal dysplasia in human beings. Am J Pathol — PubMed:PMID7065114 — OMIA Phene_Article / Article
- 2004. Stomatocytosis in 7 related Standard Schnauzers. Vet Clin Pathol — PubMed:PMID15570561 | DOI:10.1111/j.1939-165x.2004.tb00379.x — OMIA Phene_Article / Article
- 2012. Cation-leak stomatocytosis in standard schnauzers does not cosegregate with coding mutations in the RhAG, SLC4A1, or GLUT1 genes associated with human disease. Blood Cells Mol Dis — PubMed:PMID22406315 | DOI:10.1016/j.bcmd.2012.02.003 — OMIA Phene_Article / Article
- 2021. Stomatocytosis in a Beagle and Australian Cattle Dog. Vet Clin Pathol — PubMed:PMID34628677 | DOI:10.1111/vcp.13001 — OMIA Phene_Article / Article
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."