--- license: permission_granted topic_id: companion_breed_health_noric_horse_omia2497_horse category: companion-breed-health title: "Noric (Horse) — Coat colour, roan (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-23 from local OMIA database dump." source_file: pdf-raw/breed-health/noric_horse_omia2497_2497.txt date_parsed: 2026-08-23 tokens_estimated: 132 verification: method: substring_match claims: 5 passed: 5 date: 2026-08-23 recovered: false path: companion-breed-health/companion_breed_health_noric_horse_omia2497_horse/01_companion_breed_health_noric_horse_omia2497_horse.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Noric (Horse) — Coat colour, roan (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA001216/9796/" retrieved: "2026-08-23" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."---
Noric (Horse) — Coat colour, roan (hereditary; OMIA-verified breed predisposition)
Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Breed: Noric (Horse)Disorder:Mode of inheritance: AutosomalDefect: noPrevalence: Grizl-Seger et al. (2020): The G -allele of the top associated SNP was present in other roan horses, namely Quarter Horse, Murgese, Slovenian, and Belgian draught horse, while it was absent in a panel of 15 breeds, including 657 non-roan horses. In further 379 gray Lipizzan horses, eight animals exhibited a heterozygous genotype (A/G).
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: c-kit (Entrez Gene ID 5430480) — OMIA Phene_Gene / GeneSynonym
- OMIA molecular-genetics note: Building on the results of work showing that dominant white coat colour in pigs is due to a mutation at the KIT gene (see OMIA 000209), Marklund (1997) reported very strong evidence that the KIT gene in horses is the gene for roan coat colour: a linkage study revealed zero recombinantion between Roan and KIT, and a 79 bp insertion between exons 1 and 2 of the KIT gene, creating a frameshift mutati…
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 1982. A linkage group composed of 3 coat colour genes and 3 serum protein loci in horses. Journal of Heredity — PubMed:PMID7096983 — OMIA Phene_Article / Article
- 1994. Parentage Testing and Linkage Analysis in the Horse Using a Set of Highly Polymorphic Microsatellites. Animal Genetics — PubMed:PMID8161016 — OMIA Phene_Article / Article
- 1999. Close association between sequence polymorphism in the KIT gene and the roan coat color in horses. Mammalian Genome — PubMed:PMID10051325 — OMIA Phene_Article / Article
- 2009. Molecular tests for coat colours in horses. J Anim Breed Genet — PubMed:PMID19912415 | DOI:10.1111/j.1439-0388.2009.00832.x — OMIA Phene_Article / Article
- 1984. Direct evidence for linkage of roan and extension loci in Belgian horses. J Hered — PubMed:PMID6481131 — OMIA Phene_Article / Article
- 1979. Lethal dominant roan in horses. Journal of Heredity — OMIA Phene_Article / Article
- 2017. Equine Color Genetics, 4th Edition. Wiley-Blackwell, Hoboken, NJ — OMIA Phene_Article / Article
- 2020. A genome-wide association analysis in Noriker horses identifies a SNP associated with roan coat color. J Equine Vet Sci — PubMed:PMID32303326 | DOI:10.1016/j.jevs.2020.102950 — OMIA Phene_Article / Article
- 2020. Coat Color Roan Shows Association with <i>KIT</i> Variants and No Evidence of Lethality in Icelandic Horses. Genes (Basel) — PubMed:PMID32580410 | DOI:10.3390/genes11060680 — OMIA Phene_Article / Article
- 2022. Roan coat color in livestock. Anim Genet — PubMed:PMID35811453 | DOI:10.1111/age.13240 — OMIA Phene_Article / Article
- 2024. Predicted genetic burden and frequency of phenotype-associated variants in the horse. Sci Rep — PubMed:PMID38600096 | DOI:10.1038/s41598-024-57872-8 — OMIA Phene_Article / Article
- 2024. Spotting the pattern: A review on white coat color in the domestic horse. Animals (Basel) — PubMed:PMID38338094 | DOI:10.3390/ani14030451 — OMIA Phene_Article / Article
- (2 additional references in OMIA)
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:184745 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:611664 (type: trait) — OMIA Group_OMIM (via OMIA_ID)