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Newfoundland — Congenital idiopathic megaesophagus (hereditary; OMIA-verified breed predisposition)

companion_breed_health_newfoundland_congenital_idiopathic_megaesophagus_dog

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--- license: permission_granted topic_id: companion_breed_health_newfoundland_congenital_idiopathic_megaesophagus_dog category: companion-breed-health title: "Newfoundland — Congenital idiopathic megaesophagus (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump." source_file: pdf-raw/breed-health/newfoundland_congenital_idiopathic_megaesophagus_1211.txt date_parsed: 2026-08-02 tokens_estimated: 100 verification: method: substring_match claims: 4 passed: 4 date: 2026-08-02 recovered: false path: companion-breed-health/companion_breed_health_newfoundland_congenital_idiopathic_megaesophagus_dog/01_companion_breed_health_newfoundland_congenital_idiopathic_megaesophagus_dog.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Newfoundland — Congenital idiopathic megaesophagus (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA000631/9615/" retrieved: "2026-08-02" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false

Newfoundland — Congenital idiopathic megaesophagus (hereditary; OMIA-verified breed predisposition)

Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

  • Breed: Newfoundland (Dog)
  • Disorder: Congenital idiopathic megaesophagus
  • Summary: For detailed information on megaoesophagus in German Shepherd dogs due to variants in the MCHR2 gene see 'a href=../../../../../../OMIA002716/9615/OMIA:002716-9615/a : Megaoesophagus, MCHR2-related in Canis lupus familiaris'
  • Defect: yes

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.

  • 1957. Regurgitation in pups. II. Megaesophagus in a pup. Journal of the American Veterinary Medical Association — PubMed:PMID13416103 — OMIA Phene_Article / Article
  • 1990. Congenital idiopathic megaesophagus in a litter of Chinese Shar-Peis - Clinical, electrodiagnostic, and pathological findings.. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Oesophageal compliance in naturally occurring canine megaoesophagus.. Aust Vet J — PubMed:PMID8280024 | DOI:10.1111/j.1751-0813.1993.tb06079.x — OMIA Phene_Article / Article
  • 1994. Megaesophagus and hypomotility associated with esophageal leiomyoma in a dog.. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Megaoesophagus in the dog and cat.. Recueil de Medecine Veterinaire — OMIA Phene_Article / Article
  • 1994. Antibodies to nicotinic acetylcholine receptors in dogs with megaoesophagus.. Aust Vet J — PubMed:PMID7945104 | DOI:10.1111/j.1751-0813.1994.tb03408.x — OMIA Phene_Article / Article
  • 1994. A clinical survey of megaesophagus in the dog.. Indian Veterinary Journal — OMIA Phene_Article / Article
  • 1995. Megaoesophagus and glucocorticoid-deficient hypoadrenocorticism in a dog. Journal of Small Animal Practice — PubMed:PMID7783439 — OMIA Phene_Article / Article
  • 1996. Vagal esophagomotor nerve function and esophageal motor performance in dogs with congenital idiopathic megaesophagus. American Journal of Veterinary Research — PubMed:PMID8725822 — OMIA Phene_Article / Article
  • 1997. Canine and feline megaesophagus. Compendium on Continuing Education for the Practicing Veterinarian — OMIA Phene_Article / Article
  • 1997. Surgical and postoperative management of canine megaesophagus [German]. Kleintierpraxis — OMIA Phene_Article / Article
  • 1997. Megaesophagus in the dog - a bibliographic review and a new classification proposal [Review] [Spanish]. Archivos de Medicina Veterinaria — OMIA Phene_Article / Article
  • (21 additional references in OMIA)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.

  • 1957. Regurgitation in pups. II. Megaesophagus in a pup. Journal of the American Veterinary Medical Association — PubMed:PMID13416103 — OMIA Phene_Article / Article
  • 1990. Congenital idiopathic megaesophagus in a litter of Chinese Shar-Peis - Clinical, electrodiagnostic, and pathological findings. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Oesophageal compliance in naturally occurring canine megaoesophagus. Aust Vet J — PubMed:PMID8280024 | DOI:10.1111/j.1751-0813.1993.tb06079.x — OMIA Phene_Article / Article
  • 1994. Megaesophagus and hypomotility associated with esophageal leiomyoma in a dog. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Megaoesophagus in the dog and cat. Recueil de Medecine Veterinaire — OMIA Phene_Article / Article
  • 1994. Antibodies to nicotinic acetylcholine receptors in dogs with megaoesophagus. Aust Vet J — PubMed:PMID7945104 | DOI:10.1111/j.1751-0813.1994.tb03408.x — OMIA Phene_Article / Article
  • 1994. A clinical survey of megaesophagus in the dog. Indian Veterinary Journal — OMIA Phene_Article / Article
  • 1995. Megaoesophagus and glucocorticoid-deficient hypoadrenocorticism in a dog. Journal of Small Animal Practice — PubMed:PMID7783439 — OMIA Phene_Article / Article
  • 1996. Vagal esophagomotor nerve function and esophageal motor performance in dogs with congenital idiopathic megaesophagus. American Journal of Veterinary Research — PubMed:PMID8725822 — OMIA Phene_Article / Article
  • 1997. Canine and feline megaesophagus. Compendium on Continuing Education for the Practicing Veterinarian — OMIA Phene_Article / Article
  • 1997. Surgical and postoperative management of canine megaesophagus [German]. Kleintierpraxis — OMIA Phene_Article / Article
  • 1997. Megaesophagus in the dog - a bibliographic review and a new classification proposal [Review] [Spanish]. Archivos de Medicina Veterinaria — OMIA Phene_Article / Article
  • (21 additional references in OMIA)

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1957. Regurgitation in pups. II. Megaesophagus in a pup. Journal of the American Veterinary Medical Association — PubMed:PMID13416103 — OMIA Phene_Article / Article
  • 1990. Congenital idiopathic megaesophagus in a litter of Chinese Shar-Peis - Clinical, electrodiagnostic, and pathological findings. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Oesophageal compliance in naturally occurring canine megaoesophagus. Aust Vet J — PubMed:PMID8280024 | DOI:10.1111/j.1751-0813.1993.tb06079.x — OMIA Phene_Article / Article
  • 1994. Megaesophagus and hypomotility associated with esophageal leiomyoma in a dog. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Megaoesophagus in the dog and cat. Recueil de Medecine Veterinaire — OMIA Phene_Article / Article
  • 1994. Antibodies to nicotinic acetylcholine receptors in dogs with megaoesophagus. Aust Vet J — PubMed:PMID7945104 | DOI:10.1111/j.1751-0813.1994.tb03408.x — OMIA Phene_Article / Article
  • 1994. A clinical survey of megaesophagus in the dog. Indian Veterinary Journal — OMIA Phene_Article / Article
  • 1995. Megaoesophagus and glucocorticoid-deficient hypoadrenocorticism in a dog. Journal of Small Animal Practice — PubMed:PMID7783439 — OMIA Phene_Article / Article
  • 1996. Vagal esophagomotor nerve function and esophageal motor performance in dogs with congenital idiopathic megaesophagus. American Journal of Veterinary Research — PubMed:PMID8725822 — OMIA Phene_Article / Article
  • 1997. Canine and feline megaesophagus. Compendium on Continuing Education for the Practicing Veterinarian — OMIA Phene_Article / Article
  • 1997. Surgical and postoperative management of canine megaesophagus [German]. Kleintierpraxis — OMIA Phene_Article / Article
  • 1997. Megaesophagus in the dog - a bibliographic review and a new classification proposal [Review] [Spanish]. Archivos de Medicina Veterinaria — OMIA Phene_Article / Article
  • (21 additional references in OMIA)

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1957. Regurgitation in pups. II. Megaesophagus in a pup. Journal of the American Veterinary Medical Association — PubMed:PMID13416103 — OMIA Phene_Article / Article
  • 1990. Congenital idiopathic megaesophagus in a litter of Chinese Shar-Peis - Clinical, electrodiagnostic, and pathological findings. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Oesophageal compliance in naturally occurring canine megaoesophagus. Aust Vet J — PubMed:PMID8280024 | DOI:10.1111/j.1751-0813.1993.tb06079.x — OMIA Phene_Article / Article
  • 1994. Megaesophagus and hypomotility associated with esophageal leiomyoma in a dog. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Megaoesophagus in the dog and cat. Recueil de Medecine Veterinaire — OMIA Phene_Article / Article
  • 1994. Antibodies to nicotinic acetylcholine receptors in dogs with megaoesophagus. Aust Vet J — PubMed:PMID7945104 | DOI:10.1111/j.1751-0813.1994.tb03408.x — OMIA Phene_Article / Article
  • 1994. A clinical survey of megaesophagus in the dog. Indian Veterinary Journal — OMIA Phene_Article / Article
  • 1995. Megaoesophagus and glucocorticoid-deficient hypoadrenocorticism in a dog. Journal of Small Animal Practice — PubMed:PMID7783439 — OMIA Phene_Article / Article
  • 1996. Vagal esophagomotor nerve function and esophageal motor performance in dogs with congenital idiopathic megaesophagus. American Journal of Veterinary Research — PubMed:PMID8725822 — OMIA Phene_Article / Article
  • 1997. Canine and feline megaesophagus. Compendium on Continuing Education for the Practicing Veterinarian — OMIA Phene_Article / Article
  • 1997. Surgical and postoperative management of canine megaesophagus [German]. Kleintierpraxis — OMIA Phene_Article / Article
  • 1997. Megaesophagus in the dog - a bibliographic review and a new classification proposal [Review] [Spanish]. Archivos de Medicina Veterinaria — OMIA Phene_Article / Article
  • (21 additional references in OMIA)

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

  • 1957. Regurgitation in pups. II. Megaesophagus in a pup. Journal of the American Veterinary Medical Association — PubMed:PMID13416103 — OMIA Phene_Article / Article
  • 1990. Congenital idiopathic megaesophagus in a litter of Chinese Shar-Peis - Clinical, electrodiagnostic, and pathological findings. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Oesophageal compliance in naturally occurring canine megaoesophagus. Aust Vet J — PubMed:PMID8280024 | DOI:10.1111/j.1751-0813.1993.tb06079.x — OMIA Phene_Article / Article
  • 1994. Megaesophagus and hypomotility associated with esophageal leiomyoma in a dog. Journal of the American Animal Hospital Association — OMIA Phene_Article / Article
  • 1993. Megaoesophagus in the dog and cat. Recueil de Medecine Veterinaire — OMIA Phene_Article / Article
  • 1994. Antibodies to nicotinic acetylcholine receptors in dogs with megaoesophagus. Aust Vet J — PubMed:PMID7945104 | DOI:10.1111/j.1751-0813.1994.tb03408.x — OMIA Phene_Article / Article
  • 1994. A clinical survey of megaesophagus in the dog. Indian Veterinary Journal — OMIA Phene_Article / Article
  • 1995. Megaoesophagus and glucocorticoid-deficient hypoadrenocorticism in a dog. Journal of Small Animal Practice — PubMed:PMID7783439 — OMIA Phene_Article / Article
  • 1996. Vagal esophagomotor nerve function and esophageal motor performance in dogs with congenital idiopathic megaesophagus. American Journal of Veterinary Research — PubMed:PMID8725822 — OMIA Phene_Article / Article
  • 1997. Canine and feline megaesophagus. Compendium on Continuing Education for the Practicing Veterinarian — OMIA Phene_Article / Article
  • 1997. Surgical and postoperative management of canine megaesophagus [German]. Kleintierpraxis — OMIA Phene_Article / Article
  • 1997. Megaesophagus in the dog - a bibliographic review and a new classification proposal [Review] [Spanish]. Archivos de Medicina Veterinaria — OMIA Phene_Article / Article
  • (21 additional references in OMIA)

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Sources

Newfoundland — Congenital idiopathic megaesophagus (hereditary; OMIA-verified breed predisposition)
companion-breed-healthPMID 13416103

Machine access

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