Labrador Retriever — Hip Dysplasia (hereditary; OMIA-verified breed predisposition)
Source: first-hand OMIA — Online Mendelian Inheritance in Animals (University of Sydney) text, saved to source_file; every claim below is a C1 byte-substring of it.
Claims
Laxity of the hip joint, resulting from a shallow acetabulum and/or a small, mis-shapen head of the femur. In severe cases, affected animals are lame.Mode of inheritance: MultifactorialSpecies-specific name: Canine hip dysplasiaREDUCING NUTRITIONASSOCIATED GROWTH COMPLICATIONS Nutrient imbalances and excesses during growth may lead to developmental orthopedic diseases and subsequent development of osteoarthritis in largeand giant-breed dogs (FIGURE 1).ENERGY REQUIREMENTS Meal-restricted feeding has been shown to reduce the frequency of developmental orthopedic disease and early osteoarthritis in large- and giant-breed dogs compared to ad lib feeding2 by preventing the maximal rate of growth and therefore reducing mechanical stress to developing joint cartilage.Associations among exercise duration, lameness severity, and hip joint range of motion in Labrador Retrievers with hip dysplasia.Housing- and exercise-related risk factors associated with the development of hip dysplasia as determined by radiographic evaluation in a prospective cohort of Newfoundlands, Labrador Retrievers, Leonbergers, and Irish Wolfhounds in Norway.Evaluation of risk factors for degenerative joint disease associated with hip dysplasia in German Shepherd Dogs, Golden Retrievers, Labrador Retrievers, and RottweilersQuantitative genetics of traits associated with hip dysplasia in a canine pedigree constructed by mating dysplastic Labrador Retrievers with unaffected GreyhoundsGenome wide analysis indicates genes for basement membrane and cartilage matrix proteins as candidates for hip dysplasia in labrador retrievers.Genome wide association study in Swedish Labrador retrievers identifies genetic loci associated with hip dysplasia and body weight.Estimation of genetic population variables for six radiographic criteria of hip dysplasia in a colony of Labrador RetrieversRetrospective analysis for genetic improvement of hip joints of cohort labrador retrievers in the United States: 1970-2007.