Japanese Bobtail — Bobtail, bobbed tail (hereditary; OMIA-verified breed predisposition)

--- license: permission_granted topic_id: companion_breed_health_japanese_bobtail_bobtail_bobbed_tail_cat category: companion-breed-health title: "Japanese Bobtail — Bobtail, bobbed tail (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump." source_file: pdf-raw/breed-health/japanese_bobtail_bobtail_bobbed_tail_3819.txt date_parsed: 2026-08-02 tokens_estimated: 362 verification: method: substring_match claims: 7 passed: 7 date: 2026-08-02 recovered: false path: companion-breed-health/companion_breed_health_japanese_bobtail_bobtail_bobbed_tail_cat/01_companion_breed_health_japanese_bobtail_bobtail_bobbed_tail_cat.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Japanese Bobtail — Bobtail, bobbed tail (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA001987/9685/" retrieved: "2026-08-02" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false

Japanese Bobtail — Bobtail, bobbed tail (hereditary; OMIA-verified breed predisposition)

Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.

Claims

Breed: Japanese Bobtail (Cat)
Disorder: Bobtail, bobbed tail
Mode of inheritance: Autosomal dominant
Summary: Japanese Bobtail cats have such a shortened and kinked tail. Show-quality standards require the cat to have a tail length under 3 inches (Pollard et al., 2015). The shortened tail in this breed is caused by a different mutation and gene compared to the tailless Manx phenotype (a href=https://omia.org/OMIA000975/9685/OMIA:000975-9685/a).
Clin feat: Pollard et al. (2015): radiological examinations of the entire vertebral column of kink-tailed cats indicated variation from the normal vertebral feline formula (C7, T13, L7, S3, Cd20-24), including cats with mostly one reduction of thoracic vertebrae (C7, T12, L7, S3), and an average of 15.8 caudal vertebrae. A few cats had variation in the number of cervical vertebrae. Several transitional vertebrae and anomalous ribs were noted. One cat had a bifid vertebra in the tail. Most cats had hemivertebrae that were usually included in the tail kink, one of which was demonstrated by gross pathology and histopathology. The abnormal vertebral formula or the placement of the kink in the tail did not coincide with morbidity or mortality.
Defect: yes
Prevalence: As reported by Lyon et al. (2016): A sub-set of cats was genotyped for the HES7 variant, supporting the variant as private to the Japanese bobtail breed.

Associated gene(s)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

Gene: Entrez Gene ID 389713779 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
OMIA molecular-genetics note: Lyons et al. (2016): c.5A>G; p.V2A (omia.variant:145) in Japanese Bobtail Xu et al. (2016) identified the same likely causal mutation in Chinese short-tailed feral cat, and confirmed it in Japanese Bobtail.

Evidence (references)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

2016. Whole genome sequencing in cats, identifies new models for blindness in AIPL1 and somite segmentation in HES7. BMC Genomics — PubMed:PMID27030474 | DOI:10.1186/s12864-016-2595-4 — OMIA Phene_Article / Article
2015. Japanese Bobtail: vertebral morphology and genetic characterization of an established cat breed. J Feline Med Surg — PubMed:PMID25488973 | DOI:10.1177/1098612X14558147 — OMIA Phene_Article / Article
2016. Whole genome sequencing identifies a missense mutation in HES7 associated with short tails in Asian domestic cats. Sci Rep — PubMed:PMID27560986 | DOI:10.1038/srep31583 — OMIA Phene_Article / Article
2021. A domestic cat whole exome sequencing resource for trait discovery. Sci Rep — PubMed:PMID33785770 | DOI:10.1038/s41598-021-86200-7 — OMIA Phene_Article / Article
2022. Genetic epidemiology of blood type, disease and trait variants, and genome-wide genetic diversity in over 11,000 domestic cats. PLoS Genet — PubMed:PMID35709088 | DOI:10.1371/journal.pgen.1009804 — OMIA Phene_Article / Article

Comparative medicine (human OMIM)

Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.

OMIM:608059 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
OMIM:613686 (type: trait) — OMIA Group_OMIM (via OMIA_ID)

verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."

Japanese Bobtail — Bobtail, bobbed tail (hereditary; OMIA-verified breed predisposition)