--- license: permission_granted topic_id: companion_breed_health_black_and_tan_coonhound_fxiii_dog category: companion-breed-health title: "Black and Tan Coonhound — FXIII (hereditary; OMIA-verified breed predisposition)" lang: en source: "OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump." source_file: pdf-raw/breed-health/black_and_tan_coonhound_fxiii_6882.txt date_parsed: 2026-08-02 tokens_estimated: 111 verification: method: substring_match claims: 5 passed: 5 date: 2026-08-02 recovered: false path: companion-breed-health/companion_breed_health_black_and_tan_coonhound_fxiii_dog/01_companion_breed_health_black_and_tan_coonhound_fxiii_dog.md source_document: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" citation: authority: "OMIA — Online Mendelian Inheritance in Animals (University of Sydney)" title: "Black and Tan Coonhound — FXIII (hereditary; OMIA-verified breed predisposition)" url: "https://omia.org/OMIA001818/9615/" retrieved: "2026-08-02" ref: "OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70" doc_type: "academic animal-genetics database (breed-specific disorder entries)" needs_review: false
Black and Tan Coonhound — FXIII (hereditary; OMIA-verified breed predisposition)
Source: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; every claim below is a C1 byte-substring of it.
Claims
Breed: Black and Tan Coonhound (Dog)Disorder: FXIIIMode of inheritance: Probably autosomal recessiveClin feat: Pieples et al. (2026): A 4-month-old male Black and Tan Coonhound presented with spontaneous hemoperitoneum, thrombocytopenia, and persistent bleeding after surgical procedures. .... A functional FXIII deficiency was identified ... .Defect: yes
Associated gene(s)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- Gene: Entrez Gene ID 398299111 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene
- OMIA molecular-genetics note: Pieples et al. (2026) identified a homozygous variant (c.1234_1239delinsTCAA) in exon 11 of F13A1 (omia.variant:1910) that predicts a frameshift and premature stop codon as likely causal variant in a Black and Tan Coonhound.
Evidence (references)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- 2026. Identification of an F13A1 frameshift variant associated with factor XIII deficiency in a Coonhound dog with severe coagulopathy. J Vet Intern Med — PubMed:PMID42184124 | DOI:10.1093/jvimsj/aalag093 — OMIA Phene_Article / Article
- 2014. Recurrent episodes of severe bleeding caused by congenital factor XIII deficiency in a dog. J Am Vet Med Assoc — PubMed:PMID25356716 | DOI:10.2460/javma.245.10.1147 — OMIA Phene_Article / Article
Comparative medicine (human OMIM)
Derived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.
- OMIM:613225 (type: trait) — OMIA Group_OMIM (via OMIA_ID)
- OMIM:134570 (type: gene) — OMIA Group_OMIM (via OMIA_ID)
verification_derived: method: derived_from_dataset source: "OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM" note: "Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose."