公告168 药物饲料添加剂目录 × FDA ADE：硫酸安普霉素预混剂（Apramycin Sulfate Premix）
Cross-reference between China's veterinary medicinal feed-additive directory (农业部公告第168号《饲料药物添加剂使用规范》) and the US FDA CVM adverse-event (ADE) report database (openFDA animalandveterinary/event.json). This is a structural link, not a clinical assertion.
Directory entry (公告168, first-hand MOFCOM PDF)
- 中文名：硫酸安普霉素预混剂
- English name：Apramycin Sulfate Premix
- 有效成分（active ingredient）：apramycin（混饲。每 1000kg 饲料添加 80-100g(以有效成分计)，连用 7）
- 所属目录：附录二（防治用，须遵守休药期）
- 适用动物：猪
- 作用与用途：用于畜禽肠道革兰氏阴性菌感染。
OpenFDA ADE cross-reference
- OpenFDA ADE 报告数：12（截至 2026-08-16，openFDA animalandveterinary/event.json 中以“apramycin”为活性成分检出的不良事件报告总数，报告级聚合）。
- 对应站内 FDA ADE topic：[ade_apramycin_adverse_events](../../ade/ade_apramycin_adverse_events/01_apramycin.md)
Honest scope note
公告168 was repealed for growth-promotion use by 公告194 (2019/2020); its directory remains the authoritative list of veterinary medicinal feed additives. OpenFDA data is US-reported and may not include China-specific products or trade names; an ADE count reflects spontaneous reporting volume, not incidence or per-animal risk. Active-ingredient→OpenFDA term mapping is editorial. Source: MOFCOM PDF cn_medical_feed_additive_dir_ann168_mofcom.pdf + openFDA slice cn_ade_crossref_2026-08-16.json (both pulled 2026-08-16).