Source
APVMA PubCRIS search results — keyword "dog", category "vetchem", retrieved via Tokyo VPS relay on 2026-07-21. Source URL: https://portal.apvma.gov.au/pubcris.
Product Overview
Purina TotalCare Heartwormer, Wormer & Flea Protection is a registered veterinary combination product line providing three-in-one parasite control: heartworm prevention (*Dirofilaria immitis*), intestinal wormer activity, and flea (and in some SKUs, tick) control. The active constituents are MOXIDECTIN (macrocyclic lactone endectocide) and IMIDACLOPRID (neonicotinoid ectoparasiticide).
Product type: PARASITICIDES; registration status: Registered for all SKUs.
Source text: MOXIDECTIN | IMIDACLOPRID
Products Listed
| APVMA Product No. | Product Name | Active Constituents | |
|---|---|---|---|
| 95597 | Purina TotalCare Heartwormer, Wormer & Flea Protection for Large Dogs | MOXIDECTIN \ | IMIDACLOPRID |
| 95596 | Purina TotalCare Heartwormer, Wormer & Flea Protection for Medium Dogs | MOXIDECTIN \ | IMIDACLOPRID |
| 95595 | Purina TotalCare Heartwormer, Wormer & Flea Protection for Small Dogs | MOXIDECTIN \ | IMIDACLOPRID |
Source text from PubCRIS result rows:
95597/Purina TotalCare Heartwormer, Wormer & Flea Protection for Large Dogs/PARASITICIDES/Registered/MOXIDECTIN | IMIDACLOPRID95596/Purina TotalCare Heartwormer, Wormer & Flea Protection for Medium Dogs/PARASITICIDES/Registered/MOXIDECTIN | IMIDACLOPRID95595/Purina TotalCare Heartwormer, Wormer & Flea Protection for Small Dogs/PARASITICIDES/Registered/MOXIDECTIN | IMIDACLOPRID
Active Constituent Roles
- MOXIDECTIN: second-generation milbemycin macrocyclic lactone — microfilaricidal and larvicidal action against *D. immitis*; also effective against *Ancylostoma* spp. and *Toxocara* spp.
- IMIDACLOPRID: neonicotinoid — adulticidal activity against fleas (*Ctenocephalides felis*, *C. canis*); some tick control activity depending on formulation
Source text: MOXIDECTIN | IMIDACLOPRID — verified verbatim from PubCRIS result cells.
Claims (Key Facts, substring-verified)
- Active constituents: "MOXIDECTIN | IMIDACLOPRID" — confirmed verbatim in PubCRIS result rows for products 95597, 95596, 95595
- Product type: "PARASITICIDES" — confirmed for all three products
- Registration status: "Registered" — confirmed for all three products
- Three SKUs: Large Dogs (95597), Medium Dogs (95596), Small Dogs (95595) — each with a distinct APVMA product number, confirmed in result rows
- Product line name: "Purina TotalCare Heartwormer, Wormer & Flea Protection" — confirmed in product name field of result rows
Related Topics
apvma_pubcris_milbemycin_oxime_lotilaner_advocate_select— Milbemycin Oxime + Lotilaner Advocate product lineapvma_pubcris_fluralaner_milbemycin_bravecto_combo— Fluralaner + Milbemycin Oxime Bravecto 1-Month
Source Citation
Source: APVMA PubCRIS Public Chemical Registration Information System URL: https://portal.apvma.gov.au/pubcris Extracted: 2026-07-21 via Tokyo VPS relay (206.237.120.227) Source file: pdf-raw/au-2026/apvma-pubcris-search-dog-vetchem-20260721.html