Xylazine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Xylazine is a active ingredient.
Total reports
Xylazine: 985
Reports by species (top entries)
- Horse 384
- Dog 232
- Cat 138
- Cattle 44
- Other 30
- Mouse 19
Top reported reactions (VEDDRA terms, top entries)
- INEFFECTIVE, SEDATION 224
- Death 206
- Lack of efficacy - NOS 105
- INEFFECTIVE, ANESTHESIA 99
- Convulsion 42
- Death by euthanasia 39
- Recovery prolonged 36
- Collapse (see also 'Cardio-vascular' and 'Systemic disorders') 33
- Apnoea 31
- Ataxia 31
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b11.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).