tris-edta — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-08-16. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. "tris-edta" is a name as filed in the drug active-ingredient field of these reports (may be a generic ingredient or a product/brand name as reported).
Total reports
tris-edta: 247
Reports by species (top entries)
- Dog 219
- Cat 24
- Human 4
Top reported reactions (VEDDRA terms, top entries)
- Lack of efficacy - NOS 52
- Vomiting 31
- Ataxia 22
- Head tilt - ear disorder 22
- Other abnormal test result NOS 19
- Decreased appetite 18
- Behavioural disorder NOS 17
- Nystagmus 17
- Diarrhoea 16
- Ear pain 16
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-08-16_b1.json (openFDA animalandveterinary/event.json, pulled 2026-08-16).