Topiramate — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Topiramate is a active ingredient.
Total reports
Topiramate: 13
Reports by species (top entries)
- Dog 7
- Human 6
Top reported reactions (VEDDRA terms, top entries)
- Accidental exposure 4
- Abdominal pain 2
- Ataxia 2
- Focal seizure 2
- Increased seizure frequency 2
- Other abnormal test result NOS 2
- Seizure NOS 2
- Stomach pain 2
- Anaemia NOS 1
- Appetite loss 1
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b31.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).