FDA ADE — Top Reported Active Ingredients in Cats
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level and not additive. This topic ranks the active ingredients most frequently named in adverse-event reports where the affected animal species is Cat. Active-ingredient names are verbatim from openFDA's drug.active_ingredients.name field (combo products appear as combined terms, e.g. "Pyrantel Pamoate;Sarolaner").
Total Cat adverse-event reports
Cat: 148091
Top reported active ingredients (Cat)
- Selamectin 21951
- Spinosad 11858
- Praziquantel 10409
- Fluralaner Spot-On Solution 10109
- Nitenpyram 8656
- Selamectin;Sarolaner 7793
- Frunevetmab 7616
- Imidacloprid 6827
- Moxidectin 6380
- Cefovecin 5650
- Buprenorphine 5308
- Emodepside 4612
- Velagliflozin Proline Monohydrate 4051
- Bexagliflozin 3770
- Meloxicam 3587
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_species_active_2026-07-22.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).