Tobramycin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Tobramycin is a active ingredient.
Total reports
Tobramycin: 179
Reports by species (top entries)
- Dog 115
- Cat 61
- Monkey 1
- Rabbit 1
Top reported reactions (VEDDRA terms, top entries)
- Corneal ulcer 39
- Lethargy (see also Central nervous system depression in 'Neurological') 35
- Ocular discharge 29
- Anorexia 27
- Other abnormal test result NOS 26
- Corneal disorder NOS 25
- Neutrophilia 21
- Vomiting 21
- Death by euthanasia 20
- Keratoconjunctivitis sicca 18
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b19.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).