Thyroxine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Thyroxine is a active ingredient.
Total reports
Thyroxine: 302
Reports by species (top entries)
- Dog 299
- Cat 2
- Human 1
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 53
- Lethargy (see also Central nervous system depression in 'Neurological') 49
- Other abnormal test result NOS 39
- Diarrhoea 33
- Anorexia 28
- Elevated alanine aminotransferase (ALT) 27
- Death by euthanasia 23
- Polydipsia 23
- Elevated serum alkaline phosphatase (SAP) 22
- Weight loss 22
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b16.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).