Sildenafil — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Sildenafil is a active ingredient.
Total reports
Sildenafil: 67
Reports by species (top entries)
- Dog 64
- Cat 2
- Human 1
Top reported reactions (VEDDRA terms, top entries)
- Not eating 12
- Lethargy (see also Central nervous system depression in Neurological) 10
- Death by euthanasia 8
- Hyperkalaemia 7
- Behavioural disorder NOS 6
- Death 6
- Lack of efficacy - NOS 6
- Abnormal radiograph finding 5
- Decreased appetite 5
- Diarrhoea 5
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b23.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).