Sevoflurane — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Sevoflurane is a active ingredient.
Total reports
Sevoflurane: 1296
Reports by species (top entries)
- Dog 808
- Cat 374
- Human 19
- Horse 14
- Other 13
- Rabbit 9
Top reported reactions (VEDDRA terms, top entries)
- Death 334
- Cardiac arrest 219
- Apnoea 175
- Bradycardia 135
- Vomiting 109
- Anorexia 90
- Lethargy (see also Central nervous system depression in 'Neurological') 89
- INEFFECTIVE, ANESTHESIA 87
- Hypothermia 54
- Tachycardia 54
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b11.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).