FDA ADE reports for Selegiline (MAO-B inhibitor (canine cognitive dysfunction, Cushing's)) — total reports, species & reaction breakdown

ade_selegiline_adverse_events

ade en 2026-07-22

Selegiline — FDA Animal & Veterinary Adverse Event (ADE) Reports

Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Selegiline is a MAO-B inhibitor (canine cognitive dysfunction, Cushing's).

Total reports

Selegiline: 4321

Reports by species (top entries)

Dog 3942
Human 46
Cat 37
Other 2
Parrot 1

Top reported reactions (VEDDRA terms, top entries)

Vomiting 439
INEFFECTIVE, COGNITIVE DYSFUNC 403
INEFFECTIVE, LOSS OF EFFECT 333
Diarrhoea 324
Anorexia 320
Lack of efficacy - NOS 307
Depression 306
INEFFECTIVE, CUSHINGS 243
Restlessness 243
Death by euthanasia 240

"Lack of efficacy" terms denote product-performance reports, not adverse reactions.

Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).

Sources

openFDA animalandveterinary/event.json (FDA CVM ADE), pulled 2026-07-22

Machine access

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