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FDA ADE reports for Pyriproxyfen

ade_pyriproxyfen_adverse_events

ade en 2026-07-22

Pyriproxyfen — FDA Animal & Veterinary Adverse Event (ADE) Reports

Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Pyriproxyfen is a active ingredient.

Total reports

Pyriproxyfen: 1452

Reports by species (top entries)

  • Dog 956
  • Cat 487
  • Human 6
  • Rabbit 1

Top reported reactions (VEDDRA terms, top entries)

  • Lack of efficacy (ectoparasite) - flea 378
  • Pruritus 298
  • Lethargy (see also Central nervous system depression in 'Neurological') 165
  • Vomiting 150
  • Behavioural disorder NOS 138
  • Diarrhoea 85
  • Anorexia 69
  • Application site pruritus 65
  • Seizure NOS 61
  • Other abnormal test result NOS 58

Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b10.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).

Sources

FDA ADE reports for Pyriproxyfen (active ingredient) — total reports, species & reaction breakdown
Source document: FDA FAERS / openFDA Animal & Veterinary Event Reports
US FDA Center for Veterinary Medicine (openFDA animal & veterinary event database)retrieved 2026-07-22

Verification file: pdf-raw/ade/ade_active_ingredients_2026-07-22_b10.json

Link points to the issuing authority's site; a direct document link is still being verified.