Progesterone — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Progesterone is a active ingredient.
Total reports
Progesterone: 841
Reports by species (top entries)
- Cattle 482
- Sheep 28
- Human 22
- Goat 18
- Dog 7
- Horse 5
Top reported reactions (VEDDRA terms, top entries)
- INEFFECTIVE, ESTRUS SYNCHRONIZ 237
- Lack of efficacy - NOS 116
- Insert, Damaged 62
- Product Defect, General 53
- Containers, Damaged 48
- Insert, Abnormal 36
- Underfilling, Package 35
- Implant, Abnormal 34
- Rectal prolapse 33
- Death 32
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b12.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).