Polymyxin B — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Polymyxin B is a active ingredient.
Total reports
Polymyxin B: 871
Reports by species (top entries)
- Dog 751
- Cat 35
- Human 4
- Horse 1
Top reported reactions (VEDDRA terms, top entries)
- Loss of hearing 205
- Deafness 157
- Lack of efficacy - NOS 101
- Impaired hearing 80
- Hearing decreased 68
- Behavioural disorder NOS 41
- Vomiting 38
- Ear discharge 37
- Ear infection NOS 33
- Partial deafness 31
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b12.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).