Poloxalene — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Poloxalene is a active ingredient.
Total reports
Poloxalene: 33
Reports by species (top entries)
- Cattle 16
- Human 3
- Goat 2
- Horse 2
- Sheep 1
Top reported reactions (VEDDRA terms, top entries)
- Death 6
- Lack of efficacy - NOS 5
- Accidental exposure 4
- Unclassifiable adverse event 4
- Death by euthanasia 3
- Depression 3
- Ruminal bloat 3
- Color, Abnormal 2
- Diarrhoea 2
- No sign 2
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b26.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).