Piperazine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Piperazine is a active ingredient.
Total reports
Piperazine: 39
Reports by species (top entries)
- Dog 20
- Cat 17
- Horse 2
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 13
- Death 7
- Depression 7
- Twitching 7
- Accidental exposure 6
- Ataxia 6
- Anorexia 4
- Convulsion 4
- Hypersalivation 4
- No sign 4
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b27.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).