Permethrin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Permethrin is a active ingredient.
Total reports
Permethrin: 664
Reports by species (top entries)
- Dog 627
- Cat 22
- Cattle 13
- Goat 1
Top reported reactions (VEDDRA terms, top entries)
- Lack of efficacy (ectoparasite) - flea 161
- Pruritus 103
- Vomiting 73
- Behavioural disorder NOS 66
- Lethargy (see also Central nervous system depression in 'Neurological') 65
- Diarrhoea 49
- Application site pruritus 42
- Other abnormal test result NOS 40
- Agitation 32
- Anorexia 32
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b12.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).