Ophiopogon Japonicus Root Extract — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Ophiopogon Japonicus Root Extract is a active ingredient.
Total reports
Ophiopogon Japonicus Root Extract: 56
Reports by species (top entries)
- Dog 46
- Cat 7
- Human 3
Top reported reactions (VEDDRA terms, top entries)
- Application site erythema 17
- Application site pruritus 9
- Lack of efficacy - NOS 6
- Pruritus 4
- Application site irritation 3
- Flaking skin 3
- Application site itching 2
- Application site scab 2
- Hives (see also 'Skin') 2
- Hot spot (pyotraumatic dermatitis) 2
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b23.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).