Ondansetron — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Ondansetron is a active ingredient.
Total reports
Ondansetron: 636
Reports by species (top entries)
- Dog 456
- Cat 176
- Human 3
- Lynx 1
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 168
- Lethargy (see also Central nervous system depression in Neurological) 159
- Death by euthanasia 125
- Diarrhoea 121
- Not eating 120
- Elevated alanine aminotransferase (ALT) 86
- Decreased appetite 79
- Weight loss 78
- Other abnormal test result NOS 76
- Elevated total bilirubin 72
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b13.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).