Omeprazole — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-21. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Omeprazole is a proton-pump inhibitor (gastric ulcer).
Total reports
Omeprazole: 3665
Reports by species (top entries)
- Horse 1821
- Dog 920
- Human 46
- Cat 36
- Pig 5
- Mule 2
Top reported reactions (VEDDRA terms, top entries)
- Lack of efficacy - NOS 840
- INEFFECTIVE, GASTRIC ULCER(S) 809
- Vomiting 292
- Partial lack of efficacy 220
- Diarrhoea 219
- Locking Mechanism Abnormal 191
- Death by euthanasia 164
- Anorexia 162
- Lethargy (see also Central nervous system depression in 'Neurological') 160
- Other abnormal test result NOS 146
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-21.json (openFDA animalandveterinary/event.json, pulled 2026-07-21).