Niacinamide — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Niacinamide is a active ingredient.
Total reports
Niacinamide: 51
Reports by species (top entries)
- Dog 50
- Human 1
Top reported reactions (VEDDRA terms, top entries)
- Diarrhoea 8
- Lethargy (see also Central nervous system depression in 'Neurological') 6
- Vomiting 6
- Anorexia 5
- Lack of efficacy - NOS 5
- Lethargy (see also Central nervous system depression in Neurological) 5
- Seizure NOS 5
- Elevated alanine aminotransferase (ALT) 4
- Leucocytosis NOS 4
- Not eating 4
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b24.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).