Moxidectin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-21. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Moxidectin is a veterinary active ingredient.
Total reports
Moxidectin: 96700
Reports by species (top entries)
- Dog 73342
- Cat 11233
- Horse 1735
- Cattle 1314
- Human 1013
- Goat 96
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 15176
- Lack of efficacy (endoparasite) - heartworm 10774
- Lethargy (see also Central nervous system depression in 'Neurological') 6520
- Diarrhoea 6165
- Lack of efficacy (endoparasite) - hookworm 5586
- Anaphylaxis 5115
- Pruritus 4153
- Facial swelling (see also 'Skin') 3736
- Anorexia 3729
- Lack of efficacy (ectoparasite) - flea 3463
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-21.json (openFDA animalandveterinary/event.json, pulled 2026-07-21).