Mirtazapine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Mirtazapine is a veterinary active ingredient.
Total reports
Mirtazapine: 2834
Reports by species (top entries)
- Cat 1786
- Dog 278
- Human 54
- Fallow 1
- Other 1
- Tiger 1
Top reported reactions (VEDDRA terms, top entries)
- Death by euthanasia 303
- Lack of efficacy - NOS 296
- Vomiting 281
- Appearance, Abnormal 267
- Product defect, product difficult to use/handle (see also 'Drug device difficult to use/handle') 249
- Tubes, Leaking 235
- Weight loss 221
- Anorexia 218
- Lethargy (see also Central nervous system depression in 'Neurological') 191
- Not eating 188
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b5.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).