Milbemycin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Milbemycin is a active ingredient.
Total reports
Milbemycin: 23171
Reports by species (top entries)
- Dog 21503
- Cat 173
- Human 113
- Other 55
- Ferret 2
- 1
Top reported reactions (VEDDRA terms, top entries)
- INEFFECTIVE, HEARTWORM LARVAE 10179
- Vomiting 2679
- Diarrhoea 2031
- Lack of efficacy (endoparasite) - hookworm 1904
- Depression 1901
- INEFFECTIVE, ASCARIDS NOS 1869
- Lack of efficacy (endoparasite) - whipworm 1627
- Anorexia 989
- Underfilling, Package 798
- Convulsion 741
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b9.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).