Metoclopramide — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Metoclopramide is a veterinary active ingredient.
Total reports
Metoclopramide: 656
Reports by species (top entries)
- Dog 571
- Cat 79
- Rabbit 3
- Donkey 1
- Guinea Pig 1
- Human 1
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 191
- Diarrhoea 121
- Lethargy (see also Central nervous system depression in 'Neurological') 117
- Death by euthanasia 113
- Other abnormal test result NOS 104
- Anorexia 103
- Death 87
- Elevated alanine aminotransferase (ALT) 75
- Not eating 75
- Elevated total bilirubin 74
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b5.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).