Methotrexate — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Methotrexate is a active ingredient.
Total reports
Methotrexate: 3
Reports by species (top entries)
- Human 3
Top reported reactions (VEDDRA terms, top entries)
- Accidental exposure 2
- Diarrhoea 1
- Other abnormal test result NOS 1
- Tingling sensation 1
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b34.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).