Metformin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Metformin is a active ingredient.
Total reports
Metformin: 41
Reports by species (top entries)
- Human 37
- Horse 2
- Monkey 1
Top reported reactions (VEDDRA terms, top entries)
- Accidental exposure 20
- Nausea 7
- Diarrhoea 5
- Bad taste 4
- Abdominal pain 3
- Itching 3
- Tingling sensation 3
- Belching 2
- Burning sensation (skin) 2
- Dizziness 2
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b25.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).