Melengestrol — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Melengestrol is a active ingredient.
Total reports
Melengestrol: 763
Reports by species (top entries)
- Cattle 731
- Sheep 2
- Human 1
- Other Deer 1
Top reported reactions (VEDDRA terms, top entries)
- INEFFECTIVE, ESTRUS SUPPRESSIO 519
- Inappropriate preparation of medication 93
- Lack of efficacy - NOS 83
- Death 43
- No sign 36
- Increased sexual interest 21
- INEFFECTIVE, ESTRUS SYNCHRONIZ 19
- Lameness 19
- Pneumonia 14
- Death by euthanasia 13
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b12.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).