FDA ADE reports for Melarsomine Dihydrochloride (arsenical immiticide (adult heartworm, Dirofilaria immitis)) — total reports, species & reaction breakdown

ade_melarsomine_dihydrochloride_adverse_events

ade en 2026-07-22

Melarsomine Dihydrochloride — FDA Animal & Veterinary Adverse Event (ADE) Reports

Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Melarsomine Dihydrochloride is a arsenical immiticide (adult heartworm, Dirofilaria immitis).

Total reports

Melarsomine Dihydrochloride: 17019

Reports by species (top entries)

Dog 16492
Human 80
Other 24
Cat 6

Top reported reactions (VEDDRA terms, top entries)

INEFFECTIVE, HEARTWORM ADULTS 2622
Lack of efficacy (endoparasite) - heartworm 2346
Vomiting 1992
Injection site swelling 1737
Injection site pain 1069
Anorexia 1060
Depression 1026
Pain NOS 904
Diarrhoea 894
Fever 810

"Lack of efficacy" terms denote product-performance reports, not adverse reactions.

Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).

Sources

openFDA animalandveterinary/event.json (FDA CVM ADE), pulled 2026-07-22

Machine access

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