Maropitant — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-21. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Maropitant is a NK-1 antagonist antiemetic (Cerenia).
Total reports
Maropitant: 16284
Reports by species (top entries)
- Dog 11527
- Cat 3707
- Human 205
- Other 7
- Rabbit 6
- 3
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 3907
- Lethargy (see also Central nervous system depression in 'Neurological') 2179
- Anorexia 2075
- Diarrhoea 1920
- Death by euthanasia 1729
- Death 1557
- Lack of efficacy - NOS 1463
- Not eating 1373
- Lethargy (see also Central nervous system depression in Neurological) 1273
- Elevated alanine aminotransferase (ALT) 1256
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-21.json (openFDA animalandveterinary/event.json, pulled 2026-07-21).