Lyme Vaccine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Lyme Vaccine is a vaccine/biologic.
Total reports
Lyme Vaccine: 638
Reports by species (top entries)
- Dog 637
Top reported reactions (VEDDRA terms, top entries)
- Lack of efficacy (bacteria) - Borrelia 217
- Vomiting 120
- Lack of efficacy (ectoparasite) - tick NOS 68
- Other abnormal test result NOS 63
- Diarrhoea 50
- Lethargy (see also Central nervous system depression in 'Neurological') 49
- Lethargy (see also Central nervous system depression in Neurological) 45
- Lack of efficacy (bacteria) - Anaplasma 27
- Emesis 26
- Panting 25
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b12.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).