loratadine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-08-16. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. "loratadine" is a name as filed in the drug active-ingredient field of these reports (may be a generic ingredient or a product/brand name as reported).
Total reports
loratadine: 102
Reports by species (top entries)
- Dog 89
- Cat 7
- Human 6
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 16
- Diarrhoea 15
- Lethargy (see also Central nervous system depression in 'Neurological') 15
- Panting 9
- Death by euthanasia 8
- Lack of efficacy - NOS 8
- Emesis 7
- Other abnormal test result NOS 7
- Polydipsia 7
- Elevated alanine aminotransferase (ALT) 6
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-08-16_b1.json (openFDA animalandveterinary/event.json, pulled 2026-08-16).