Lidocaine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Lidocaine is a active ingredient.
Total reports
Lidocaine: 363
Reports by species (top entries)
- Dog 205
- Cat 124
- Horse 9
- Pig 5
- Cattle 4
- Rabbit 3
Top reported reactions (VEDDRA terms, top entries)
- Death 64
- Vomiting 43
- Death by euthanasia 35
- Other abnormal test result NOS 35
- Lethargy (see also Central nervous system depression in 'Neurological') 31
- Behavioural disorder NOS 30
- Diarrhoea 30
- Tachycardia 28
- Lack of efficacy - NOS 27
- Lethargy (see also Central nervous system depression in Neurological) 27
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b16.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).