Leptospira Canicola Bacterin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Leptospira Canicola Bacterin is a active ingredient.
Total reports
Leptospira Canicola Bacterin: 53
Reports by species (top entries)
- Cattle 52
- Goat 1
Top reported reactions (VEDDRA terms, top entries)
- Death 24
- Lack of efficacy - NOS 22
- Necropsy performed 7
- Lack of efficacy (bacteria) - NOS 4
- Death by euthanasia 3
- Lack of efficacy (virus) - NOS 3
- Lack of efficacy (virus) - bovine viral diarrhoea virus 3
- Abortion 2
- CULTURE/TITER DATA ABNORMAL 2
- Injection site lump 2
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b24.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).