Lactulose — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Lactulose is a active ingredient.
Total reports
Lactulose: 285
Reports by species (top entries)
- Cat 194
- Dog 89
- Human 1
- Other Birds 1
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 47
- Lethargy (see also Central nervous system depression in 'Neurological') 44
- Anorexia 32
- Death by euthanasia 32
- Constipation 30
- Weight loss 28
- Diarrhoea 26
- Other abnormal test result NOS 26
- Decreased appetite 25
- Lack of efficacy - NOS 25
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b16.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).