FDA ADE reports for Isoflurane (inhaled maintenance anesthetic) — total reports, species & reaction breakdown

ade_isoflurane_adverse_events

ade en 2026-07-22

Isoflurane — FDA Animal & Veterinary Adverse Event (ADE) Reports

Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Isoflurane is a inhaled maintenance anesthetic.

Total reports

Isoflurane: 5033

Reports by species (top entries)

Dog 2655
Cat 1953
Human 89
Other 72
Horse 46
Rabbit 43

Top reported reactions (VEDDRA terms, top entries)

Death 736
Vomiting 417
Cardiac arrest 408
Bradycardia 386
INEFFECTIVE, ANESTHESIA 364
Anorexia 334
Lethargy (see also Central nervous system depression in 'Neurological') 332
Not eating 306
Behavioural disorder NOS 277
Lack of efficacy - NOS 247

"Lack of efficacy" terms denote product-performance reports, not adverse reactions.

Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).

Sources

openFDA animalandveterinary/event.json (FDA CVM ADE), pulled 2026-07-22

Machine access

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