Hydroxyzine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Hydroxyzine is a active ingredient.
Total reports
Hydroxyzine: 1005
Reports by species (top entries)
- Dog 972
- Cat 16
- Human 9
- Horse 3
Top reported reactions (VEDDRA terms, top entries)
- Emesis 213
- Vomiting 169
- Lethargy (see also Central nervous system depression in 'Neurological') 128
- Diarrhoea 84
- Other abnormal test result NOS 78
- Lack of efficacy - NOS 74
- Elevated serum alkaline phosphatase (SAP) 45
- Behavioural disorder NOS 43
- Elevated alanine aminotransferase (ALT) 43
- Seizure NOS 42
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b11.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).