Hydrocodone — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Hydrocodone is a active ingredient.
Total reports
Hydrocodone: 273
Reports by species (top entries)
- Dog 263
- Human 8
- Cat 2
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 45
- Death by euthanasia 35
- Cough 34
- Lethargy (see also Central nervous system depression in 'Neurological') 31
- Diarrhoea 29
- Death 26
- Seizure NOS 25
- Panting 24
- Decreased appetite 19
- Abnormal radiograph finding 18
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b17.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).