Hyaluronate — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Hyaluronate is a active ingredient.
Total reports
Hyaluronate: 1068
Reports by species (top entries)
- Horse 497
- Dog 26
- Human 2
- Cat 1
- Other 1
- Rabbit 1
Top reported reactions (VEDDRA terms, top entries)
- Lameness 161
- Joint swelling 124
- Product syringe issue 105
- Stopper, abnormal 101
- Syringe, Abnormal 95
- Joint effusion 74
- Uncoded sign 63
- Joint pain 51
- Illness NOS 46
- Joint inflammation 45
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b11.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).