Glucosamine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Glucosamine is a active ingredient.
Total reports
Glucosamine: 1280
Reports by species (top entries)
- Dog 1209
- Cat 58
- Horse 7
- Human 3
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 233
- Lethargy (see also Central nervous system depression in 'Neurological') 209
- Emesis 155
- Diarrhoea 148
- Death by euthanasia 101
- Lack of efficacy - NOS 96
- Seizure NOS 89
- Elevated alanine aminotransferase (ALT) 85
- Anorexia 79
- Weight loss 75
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b14.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).