Fluconazole — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-21. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Fluconazole is a veterinary active ingredient.
Total reports
Fluconazole: 331
Reports by species (top entries)
- Dog 300
- Cat 27
- Parrot 2
- Human 1
- Other Birds 1
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 59
- Lethargy (see also Central nervous system depression in 'Neurological') 48
- Lack of efficacy - NOS 37
- Other abnormal test result NOS 37
- Diarrhoea 35
- Weight loss 25
- Not eating 22
- Anorexia 21
- Elevated alanine aminotransferase (ALT) 21
- Death by euthanasia 20
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-21.json (openFDA animalandveterinary/event.json, pulled 2026-07-21).