Fentanyl — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Fentanyl is a active ingredient.
Total reports
Fentanyl: 707
Reports by species (top entries)
- Dog 601
- Cat 74
- Human 9
- Goat 3
- Alpaca 2
- Pig 2
Top reported reactions (VEDDRA terms, top entries)
- Anorexia 146
- Vocalisation 111
- Death by euthanasia 91
- Hypothermia 86
- Vomiting 86
- Lethargy (see also Central nervous system depression in 'Neurological') 85
- Sedation 82
- Not eating 78
- Death 64
- Lack of efficacy - NOS 64
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b12.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).