Estrogen — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Estrogen is a active ingredient.
Total reports
Estrogen: 23
Reports by species (top entries)
- Dog 20
- Human 3
Top reported reactions (VEDDRA terms, top entries)
- Anorexia 5
- Emesis 5
- Cough 3
- Decreased appetite 3
- Elevated blood urea nitrogen (BUN) 3
- Hyperkalaemia 3
- Hypocortisolaemia 2
- Lack of efficacy - NOS 2
- Lethargy (see also Central nervous system depression in 'Neurological') 2
- Malaise 2
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b33.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).